Ten therapy areas. One integrated view of metabolic health.
Diabetes, cardiovascular disease, obesity, liver, kidney, hormonal and lifestyle factors are deeply connected. IMACH organises its scientific work into ten integrated therapy areas that reflect how these conditions occur together in real patients.
Our therapy areas.
Each area brings together related topics so that clinicians can see the whole patient — not just a single diagnosis. Overlapping cardiovascular and diabetes topics have been brought together to reflect shared mechanisms and shared treatments.
Diabetes & Its Complications
Type 1 & 2 diabetes, newer therapies, CGM, and prevention of eye, kidney, nerve, foot and heart complications.
Cardiometabolic Health & Insulin Resistance
The shared pathways — insulin resistance, visceral fat, inflammation — that link metabolic and cardiovascular disease.
Lipids & Atherosclerotic CVD
LDL targets, Lp(a), triglycerides, familial hypercholesterolaemia and prevention of atherosclerotic events.
Hypertension & Heart Failure
Blood-pressure control, vascular health, HFpEF and cardiorenal-metabolic protection.
Obesity & Weight Management
Obesity as a chronic disease: assessment beyond BMI, pharmacotherapy, surgery and long-term maintenance.
MASLD & Gut–Metabolic Health
Fatty liver disease, fibrosis assessment and the gut–liver axis and microbiome.
Kidney & Metabolic Renal Health
Early detection of CKD, kidney-protective therapies and integrated cardiorenal care.
Women’s Metabolic Health & PMOS
PMOS, gestational diabetes, pregnancy, menopause and women’s cardiovascular risk.
Endocrine, Bone & Healthy Ageing
Thyroid, adrenal and pituitary disorders, osteoporosis, frailty and multimorbidity.
Nutrition, Lifestyle & Prevention
Clinical nutrition, lifestyle medicine, preventive check-ups and sleep health.
Metabolic diseases rarely occur alone.
Shared biology
Insulin resistance, visceral adiposity, chronic inflammation and endothelial dysfunction connect diabetes, heart, liver and kidney disease.
Shared treatments
Modern therapies such as SGLT2 inhibitors and incretin-based medicines benefit several organs at once.
Shared patients
A single patient may have diabetes, hypertension, fatty liver and kidney disease simultaneously — care should reflect this.
From science to practice.
Scientific focus
Curated topics reflecting current evidence and clinical need.
Clinical pathways
Practical stage-by-stage approaches clinicians can apply.
Programmes
Masterclasses, workshops, case discussions and consensus initiatives.
Multidisciplinary faculty
Specialists from every relevant discipline.
Key questions
The open clinical questions IMACH aims to address.
Commitment
A clear statement of IMACH’s goals for each area.
At a glance.
| Therapy area | Brings together | Key specialties |
|---|---|---|
| Diabetes & Its Complications | Diabetes management; complications & long-term care | Diabetology, endocrinology, ophthalmology, nephrology, podiatry |
| Cardiometabolic Health & Insulin Resistance | Cardiometabolic health; metabolic syndrome | Cardiology, endocrinology, internal medicine |
| Lipids & Atherosclerotic CVD | Dyslipidaemia; atherosclerosis | Cardiology, lipidology, vascular medicine |
| Hypertension & Heart Failure | Hypertension; heart failure & metabolic cardiology | Cardiology, nephrology |
| Obesity & Weight Management | Obesity medicine | Endocrinology, bariatric surgery, nutrition |
| MASLD & Gut–Metabolic Health | MASLD; gut microbiome | Hepatology, gastroenterology |
| Kidney & Metabolic Renal Health | Chronic kidney disease | Nephrology, diabetology |
| Women’s Metabolic Health & PMOS | PMOS, pregnancy, menopause | Gynaecology, obstetrics, endocrinology |
| Endocrine, Bone & Healthy Ageing | Endocrinology; bone; ageing & multimorbidity | Endocrinology, orthopaedics, geriatrics |
| Nutrition, Lifestyle & Prevention | Nutrition; preventive medicine; sleep | Preventive medicine, diagnostics, nutrition, sleep |
Digital health, AI and precision medicine run across all therapy areas — see Digital Health & AI.
Contribute to a therapy area.
Clinicians and researchers can join as members, faculty or collaborators.